Urticaria could be a feature of systemic disorder: e.g. systemic lupus erythromatosis, rheumatoid arthritis, vasculitis or malignancies. This type of urticaria usually persists for more than 24 hours and may cause staining of the skin after the rash disappears. The uricaria is more painful than itchy.
Urticaria and Autoimmune Thyroid Disease
Autoimmune disease means that the body produces antibodies that attack its own cells and organs.
Chronic hives can be associated with thyroid problems. The doctor can run tests to see whether or not your thyroid is affected. It may be the cause of your urticaria.