As HAE is not an allergic condition, it won’t respond to the medications used for treatment of urticaria/angioedema. Antihistamine, epinephrine and corticosteroids are not effective.
There is no cure for HAE; management is divided into controlling the symptoms of acute attack, short term prophylaxis to prevent the attack in conditions associated with increased risk, and long term prophylaxis to decrease the frequency and severity of the attacks.
