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Test ID: Helicobacter Pylori Antigen
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Helicobacter pylori antigen
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Detection of Helicobacter pylori antigen in stool for the diagnosis of H.pylori infection
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Useful For
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Detection of Helicobacter pylori antigen in stool samples for diagnosis of H.pylori infection.
The test also can be used to determine treatment effectiveness, relapse or eradication of infection.
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Method name and description
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Commercially available Immuno-chromatographic assay
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Reporting name
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Helicobacter Pylori Antigen
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Clinical information
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Helicobacter pylori (H. pylori) is a spiral-shaped bacterium that is found in the gastric mucous layer or adherent to the epithelial lining of the stomach. H.pylori causes more than 90% of duodenal ulcers and up to 80% of gastric ulcers.
The importance of Helicobacter pylori testing has increased greatly since the strong link between the presence of bacteria and confirmed gastrointestinal diseases (stomach and duodenum) like gastric, peptic ulcer disease and gastric carcinoma was discovered.
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Aliases
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- H. pylori
- Helicobacter pylori antigen
- H. pylori Ag
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Specimen type / Specimen volume / Specimen container
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Specimen type
Specimen Volume
Specimen container
- Sterile leak proof container
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Collection instructions / Special Precautions / Timing of collection
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Collection instructions
Collect the required volume of stool into the container taking care to avoid contamination with urine or toilet water.
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Relevant clinical information to be provided
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- Any antibiotic therapy in last 4 weeks
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Storage and transport instructions
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Send immediately to the laboratory at room temperature. If any delay, then refrigerate at 2-8○C and send to the laboratory within 24 hrs of collection.
Note: Do NOT leave the specimen at room temperature for prolonged periods as this may compromise the quality of the sample
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Specimen Rejection Criteria
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- Leaking container
- Unlabeled/Mislabeled specimen
- Duplicate specimen within 48 hrs
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Biological reference intervals and clinical decision values
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Negative result
Helicobacter pylori Antigen: Negative
Positive result
Helicobacter pylori Antigen: Positive
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Factors affecting test performance and result interpretation
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Following certain antibiotic treatment, the concentration of antigen may decrease to a level below the detection limit of the test. Therefore a negative result during antibiotic therapy should be interpreted with caution.
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Turnaround time / Days and times test performed / Specimen retention time
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Turnaround time
Days and times test performed
- Sunday to Thursday 7am-3 pm only at the AAH microbiology laboratory.
Specimen retention time:
- 48 hrs after final report
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