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Test ID: Toxoplasma IgG Avidity
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Toxo IgG Avidity
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The test is lab order only
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Useful For
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The determination of the avidity of IgG antibodies to Toxoplasma gondii in human serum and plasma.
For HMC users only: This test cannot be ordered directly, it will be added by the lab for pregnant patient found to be positive for Toxo IgG & IgM.
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Method name and description
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Chemiluminescent microparticle immunoassay (CMIA)
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Aliases
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Antibody avidity - Toxo
IgG avidity index - Toxo
Toxo - antibody avidity
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Specimen type / Specimen volume / Specimen container
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Specimen type: Serum or plasma
Specimen volume: 3-5 mL.
Specimen container: Serum collected in yellow top gel tubes. Plasma collected in lithium heparin tube, Potassium EDTA tube, Sodium citrate tube, Lithium heparin tube, Sodium heparin tube.
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Collection instructions / Special Precautions / Timing of collection
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Collection by venipuncture as per organization guidelines
No special precautions / No timing of collection
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Storage and transport instructions
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Maintain specimen at 2-8°C
The specimens should be transported to Virology Section in cold box immediately
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Specimen Rejection Criteria
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Quantity of blood not sufficient
Wrong blood container
Container breakage / sample leaking
Lipemic sample
Grossly hemolyzed serum
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Biological reference intervals and clinical decision values
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No reference
High avidity / Low avidity / Grayzone
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Factors affecting test performance and result interpretation
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- Low Toxoplasma IgG avidity indicates recent infection, but
does not confirm it as risk factors for primary infection should be reviewed.
- High toxoplasma IgG avidity suggest that recent primary infection is unlikely
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Turnaround time / Days and times test performed / Specimen retention time
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Turnaround time: within 7 days
Days and times test performed: 5 days a week
Specimen retention time: 2 weeks
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