This means giving drugs for a short period of time before a surgery or other procedure that could cause an acute attack in a patient with HAE.
Oral and dental procedures are known triggers of swelling and can cause throat swelling that usually develops within 48 hours after the procedure, so C1INH concentrate is given one to two hours before and should be available for two days after.
An alternative is administration of androgens such as danazol for five days before and three days after the procedure.
