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Test ID: Acute Myeloid Leukemia Panel by FISH
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Acute Myeloid Leukemia Panel by FISH
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Acute Myeloid Leukemia Panel by FISH
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Method name and description
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Interphase Fluorescence In Situ Hybridization (I-FISH) Study
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Clinical information
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Acute Myelogenous Leukemia (AML) is a myeloid disorder branded by myeloid cell ancestry. These cells appear as persistent adjusted chromosomal modifications, following the arrangement of novel fusion proteins.
FISH test considers a set of distinctive probes comprising a board of panels to identify the foremost prognostically common and significant chromosomal anomalies, in therapy-related or repetitive AML.
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Specimen type / Specimen volume / Specimen container
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Specimen Type: Blood/Leukemic Blood:
Container/Tube: Green top (sodium heparin)
Specimen Volume: 2-6 mL (Varies depending on the WBC-Count)
(Adult - 3-6 mL ,Child - 2 mL, Infant - 2 mL)
Specimen Type: Bone marrow:
Container/Tube: Bone Marrow Transport Media
Specimen Volume: 1-3 mL (Varies depending on the WBC-Count)
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Storage and transport instructions
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Specimen Rejection Criteria
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Consistent with Diagnostic Genomic Division policies.
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Factors affecting test performance and result interpretation
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In expansion to morphology, a few repetitive chromosomal variations from the norm have been connected to subtypes of AML. The foremost common is tried by FISH for chromosome abnormalities related with AML such as, 11q23, inv(16), +8, t(8;21), t(15;17), and t(9;22).Common gene juxtaposed in modification with different other chromosomes.
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Turnaround time / Days and times test performed / Specimen retention time
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