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Test ID: T‐Cell Lymphoma Panel by FISH
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T‐Cell Lymphoma Panel by FISH
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T‐Cell Lymphoma diagnosed by FISH Test
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Useful For
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This FISH test is performed for diagnosis and treatment monitoring of T-cell Lymphoma patients with the specialized marker probes, which is established for recognizing a neoplastic clone or abnormality, found in patients having T-cell lymphomas.
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Method name and description
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Interphase Fluorescence In Situ Hybridization (I-FISH) study.
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Clinical information
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T-cell neoplasms are generally uncommon,they tend to be roughly 12% of all non-Hodgkin lymphomas.
T-Cell lymphomas are classified as, T-Cell Intense Lymphoblastic Leukemia (T-ALL), T-cell Prolymphocytic Leukemia (T-PLL), T-Cell Large Granular Lymphocytic Leukemia (T-LGL), Anaplastic Large Cell Lymphoma (ALCL), Peripheral T-cell Lymphoma, and other cutaneous, nodal, and extranodal lymphoma subtypes.
The 2 most predominant lymphoma subtypes are unspecified peripheral T-cell lymphoma (3.7%) and ALCL (2.4%). T-cell neoplasms are the most aggressive of all hematologic and lymphoid neoplasms except for ALCL, which is usually responsive to chemotherapy.
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Specimen type / Specimen volume / Specimen container
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1. Specimen Type: Blood/Leukemic Blood
Container/Tube: Green top (sodium heparin)
Specimen Volume: 2-6 mL (Varies depending on the
WBC-Count).
(Adult - 3-6 mL ,Child - 2 mL, Infant - 2 mL)
2. Specimen Type: Bone marrow
Container/Tube: Bone Marrow Transport Media
Specimen Volume: 1-3 mL (Varies depending on the
WBC-Count).
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Collection instructions / Special Precautions / Timing of collection
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Sunday-Wednesday 7:00 -14:00
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Storage and transport instructions
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Specimen Rejection Criteria
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Consistent with Diagnostic Genomic Division policies
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Factors affecting test performance and result interpretation
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Turnaround time / Days and times test performed / Specimen retention time
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