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Test ID: Non-Invasive Prenatal Testing
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Non-Invasive Prenatal Testing
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Non-Invasive Prenatal Testing (NIPT)
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Useful For
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Non-Invasive Prenatal Testing (NIPT) is a blood test performed to measure the amount of fetal cell free DNA circulating in maternal serum, this test is performed early as starting at 10 weeks of pregnancy. NIPT precisely measures the ratio of fetal and maternal chromosomal material and provides a screen risk for,
Trisomy 13 (Patau syndrome)
Trisomy 18 (Edwards syndrome)
Trisomy 21 (Down syndrome)
Common sex chromosome conditions, such as Klinefelter disorder and Turner syndrome
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Method name and description
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Non-Invasive Prenatal Testing (NIPT)
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Reporting name
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Non-Invasive Prenatal Testing
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Specimen type / Specimen volume / Specimen container
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1. Specimen Type: Whole blood/ Cord blood
Container/Tube: EDTA- Lavender top
Specimen Volume: 3-5 mL preferred, minimum 1ml
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Collection instructions / Special Precautions / Timing of collection
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Sunday to Thursday 07:00 AM to 02:00 PM.
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Storage and transport instructions
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Specimen Rejection Criteria
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Consistent with Diagnostic Genomic Division policies.
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Factors affecting test performance and result interpretation
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NIPT testing of maternal blood analyzes the fetal DNA sample ratio in the blood. The higher than expected fetal ratio of chromosome 13, 18 or 21 sequences denotes high risk of Trisomy 13 (Patau syndrome), Trisomy 18 (Edwards syndrome), or Trisomy 21 (Down syndrome).
Note: In such cases amniocentesis or CVS is performed to confirm the diagnosis
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Turnaround time / Days and times test performed / Specimen retention time
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