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Test ID: Glucose Cerebrospinal Fluid
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Glucose Cerebrospinal Fluid
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Useful For
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Evaluation of meningitis, neoplastic involvement of meninges and other neurological disorders.
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Method name and description
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UV test : Enzymatic reference method with hexokinase.
Hexokinase catalyzes the phosphorylation of glucose toglucose‑6‑phosphate by ATP. Glucose‑6‑phosphate dehydrogenase oxidizes glucose‑6‑phosphate in thepresence of NADP to gluconate‑6‑phosphate. No other carbohydrate is oxidized. The rate of NADPH formation during the reaction is directlyproportional to the glucose concentration and is measured photometrically.
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Clinical information
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Glucose is the major carbohydrate present in the peripheral blood. The glucose level in CSF is proportional to the blood glucose level and corresponds to 60-70% of the concentration in blood. CSF glucose levels can be useful in distinguishing among causes of meningitis and evaluation of neoplastic involvement of meninges and other neurological disorders.
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Specimen type / Specimen volume / Specimen container
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Specimen type: CSF
Minimum volume of sample: 1 mL
Specimen Container: Sterile container
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Collection instructions / Special Precautions / Timing of collection
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(Sample should be send and analyzed immediately.)
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Storage and transport instructions
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Storage: 4°C or -20°C
Transport: 4-8°C
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Specimen Rejection Criteria
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Insufficient sample, wrong collection container,sign of bacterial contamination.
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Biological reference intervals and clinical decision values
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0-18 years: 3.33-4.44 mmol/L
18 - 150 years: 2.22-3.89 mmol/L
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Turnaround time / Days and times test performed / Specimen retention time
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Daily (24/7)
Turn-around time:
STAT: 1 hour
Routine: One working day
Specimen Retention: 4 days
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