Dame Pamela Shaw

Professor Dame Pamela Shaw is Professor of Neurology at the University of Sheffield and Director of the Sheffield Institute for Translational Neuroscience (SITraN) and the NIHR Sheffield Biomedical Research Centre for Experimental Medicine in Neurology.  She is a Clinician Scientist, formerly a Wellcome Trust Senior Fellow and an NIHR Senior Investigator.  Her team investigates genetic, molecular and neurochemical mechanisms underlying ALS/MND; identifies new therapeutic targets and translates new therapeutic approaches into the clinic, including genetic therapy trials and identification of biomarkers of therapeutic efficacy. She has authored more than 530 publications (H-index 110), has been awarded >£110m in research income and has received many awards for her work including the DBE in 2014. Her research is funded by the NIHR, MRC, Wellcome Trust, MNDA, EU and biotech/pharmaceutical industry partners.   She established and led the national UK Clinical Studies Group for ALS/MNDlinking 20 Centres and has taken part in more than 25 ALS clinical trials.